Cancer Stem Cells

Cancer stem cells were first identified by Scientist John Dick in acute myeloid leukemia. Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that shows characteristics associated with normal stem cells, drived from tumorigenesis and gives rise to a large population of differentiated progeny that make up the bulk of the tumour, but lack tumorigenic potential, therefore they are Tumour forming. CSCs generate tumors through the stem cell processes of self-renewal and differentiate into multiple cell types. CSCs have recently been identified in several solid tumors such as in Brain, Breast, Colon, Ovary, Pancreas, Prostate, Melanoma and Multiple Myeloma

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